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. 2021 Nov 11;17(35):4883–4893. doi: 10.2217/fon-2021-0650

Table 3. . Log-rank tests and multivariable Cox regression analysis for overall survival among age-groups.

Characteristics n (%) Univariable Multivariable
  Median time (months) Log-rank p-value HR (95% CI) p-value
<50 years 5,729 (100)   <0.001    
KRAS mutated 2,391 (41.7) 23.5   Ref  
KRAS wildtype 3,338 (58.3) 28.8   0.80 (0.75–0.86) <0.001
50–69 years 14,345 (100)   <0.001    
KRAS mutated 6,226 (43.4) 21.0   Ref  
KRAS wildtype 8,119 (56.6) 23.4   0.93 (0.89–0.97) <0.001
≥70 years 6,021 (100)   0.34    
KRAS mutated 2,721 (45.2) 14.3   Ref  
KRAS wildtype 3300 (54.8) 13.9   1.00 (0.95–1.06) 0.89

HR: Hazard ratio; Ref: Reference.