Figure 5.

Improved and altered abundance of colonic taxonomic families post FMT (a) Relative abundance of the different phyla and families in the Donor wt, Recipient wt, Donor ko and Recipient ko. (b) Increase in the species richness post gavage transfer in the Recipient ko group. (c) Principal coordinate analysis depicting distinct microbial signatures between Donor ko and Recipient ko groups. (d,e.) Decrease in pro-inflammatory families Bacteroidaceae and Erysipelotrichaceae. (f) Increase in the relative abundance of Prevotellaceae and (g) protective Muribaculaceae . (h) Continued lowered abundance of Lachnospiraceae. n = 4 pairs for Donor wt, and Donor ko, n = 8 for Recipient wt and n = 7 for Recipient ko.

*p < .05, **p < .005, ***p = .0001, ****p < .0001.