Table 4.
Comparison of HR-pQCT parameters in the distal tibia between CKD stage 4–5 and CKD stage 5 D groups.
| Parameter | CKD stage 4–5 group (n = 25) | CKD stage 5D group (n = 15) | p Value |
|---|---|---|---|
| Total vBMD (mg/cm3) | 290 ± 51 | 221 ± 43 | <0.001 |
| Ct.vBMD (mg/cm3) | 842 ± 73 | 818 ± 89 | 0.39 |
| Ct.Th (mm) | 1.45 ± 0.29 | 1.18 ± 0.28 | 0.009 |
| Ct.Ar (mm2) | 133 ± 27 | 108 ± 29 | <0.001 |
| Ct.Pm (mm) | 109 ± 9 | 107 ± 13 | 0.96 |
| Ct.Po (%) | 3.8 ± 1.8 | 3.8 ± 2.2 | 0.71 |
| Ct.Po.Dm (mm) | 0.23 ± 0.03 | 0.23 ± 0.04 | 0.56 |
| Tb.vBMD (mg/cm3) | 173 ± 34 | 122 ± 39 | <0.001 |
| Tb.BV/TV (%) | 26 ± 5 | 18 ± 5 | <0.001 |
| Tb.N (1/mm) | 1.24 ± 0.18 | 1.15 ± 0.21 | 0.29 |
| Tb.Th (mm) | 0.26 ± 0.02 | 0.24 ± 0.02 | 0.001 |
| Tb.Sp (mm) | 0.79 ± 0.11 | 0.89 ± 0.24 | 0.16 |
The Wilcoxon rank-sum test was used.
Data presented as mean ± standard deviation.
CKD: chronic kidney disease; vBMD: volumetric bone mineral density; Ct.vBMD: cortical volumetric bone mineral density; Ct.Th: cortical thickness; Ct.Ar: cortical area; Ct.Pm: cortical perimeter; Ct.Po: cortical porosity; Ct.Po.Dm: cortical pore diameter; Tb.vBMD: trabecular volumetric bone mineral density; Tb.BV/TV: trabecular bone volume fraction; Tb.N: trabecular number; Tb.Th: trabecular thickness; Tb.Sp: trabecular separation.