Table 6.
Comparison of HR-pQCT parameters in the distal tibia among the three groups.
| CKD stage 4 group (n = 11) | CKD stage 5 group (n = 14) | CKD stage 5D group (n = 15) | p Value | |
|---|---|---|---|---|
| Total vBMD (mg/cm3) | 281 ± 37 | 297 ± 61 | 222 ± 43c | <0.001 |
| Ct.vBMD (mg/cm3) | 834 ± 51 | 849 ± 88 | 818 ± 89 | 0.58 |
| Ct.Th (mm) | 1.47 ± 0.20 | 1.42 ± 0.35 | 1.18 ± 0.28a | 0.02 |
| Ct.Ar (mm2) | 132 ± 22 | 133 ± 30 | 108 ± 29b | 0.03 |
| Ct.Pm (mm) | 108 ± 11 | 109 ± 8 | 107 ± 13 | 0.94 |
| Ct.Po (%) | 4.0 ± 1.4 | 3.6 ± 2.1 | 3.8 ± 2.2 | 0.89 |
| Ct.Po.Dm (mm) | 0.23 ± 0.03 | 0.23 ± 0.03 | 0.23 ± 0.04 | 0.83 |
| Tb.vBMD (mg/cm3) | 164 ± 24 | 180 ± 40 | 122 ± 39c | <0.001 |
| Tb.BV/TV (%) | 25 ± 3 | 27 ± 5 | 18 ± 5c | <0.001 |
| Tb.N (1/mm) | 1.19 ± 0.10 | 1.28 ± 0.21 | 1.15 ± 0.21 | 0.16 |
| Tb.Th (mm) | 0.26 ± 0.02 | 0.26 ± 0.02 | 0.24 ± 0.02 | 0.02 |
| Tb.Sp (mm) | 0.82 ± 0.07 | 0.76 ± 0.14 | 0.89 ± 0.24 | 0.16 |
aCKD stage 4 vs. CKD stage 5 D (p < 0.017).
bCKD stage 5 vs. CKD stage 5 D (p < 0.017).
cBoth CKD stage 4 vs. 5 D and 5 vs. 5 D (p < 0.017).
Data presented as mean ± standard deviation.
CKD: chronic kidney disease; vBMD: volumetric bone mineral density; Ct.vBMD: cortical volumetric bone mineral density; Ct.Th: cortical thickness; Ct.Ar: cortical area; Ct.Pm: cortical perimeter; Ct.Po: cortical porosity; Ct.Po.Dm: cortical pore diameter; Tb.vBMD: trabecular volumetric bone mineral density; Tb.BV/TV: trabecular bone volume fraction; Tb.N: trabecular number; Tb.Th: trabecular thickness; Tb.Sp: trabecular separation.