Table 4.

Human MHC-I epitope analysis for peptide 2.

Allele	Peptide number	MHC-I binding	Immunogenicity	Proteasome Score	TAP Score	MHC Score	Processing Score	TAP Total Score
HLA-A*02:01	2	0.02	0.18048	1.39	0.39	−0.66	1.78	1.12
HLA-B*08:01	2	0.02	0.14268	1.39	0.39	−1.31	1.78	0.47
HLA-A*23:01	2	0.03	0.19092	1.36	1.13	−1.38	2.5	1.12
HLA-A*02:03	2	0.03	0.18064	1.39	0.39	−0.91	1.78	0.87
HLA-A*24:02	2	0.04	0.19092	1.36	1.13	−1.67	2.5	0.83
HLA-A*02:06	2	0.04	0.18064	1.39	0.39	−0.96	1.78	0.82
HLA-A*33:01	2	0.09	0.18048	0.76	0.68	−1.13	1.43	0.3
HLA-B*35:01	2	0.1	0.18064	1.41	1.19	−2.35	2.6	0.25
HLA-A*03:01	2	0.12	0.18064	0.89	0.18	−1.35	1.06	−0.29
HLA-A*32:01	2	0.21	0.18064	1.39	0.39	−2.21	1.78	−0.43
HLA-B*53:01	2	0.21	0.18064	1.41	1.19	−3.4	2.6	−0.8
HLA-A*01:01	2	0.23	0.18424	1.41	1.24	−2.91	2.65	−0.26
HLA-B*15:01	2	0.29	0.18064	1.41	1.28	−1.79	2.69	0.89
HLA-A*30:02	2	0.35	0.19092	1.41	1.28	−2.29	2.69	0.4
HLA-A*31:01	2	0.45	0.18064	0.76	0.68	−1.9	1.43	−0.47
HLA-A*26:01	2	0.52	0.18048	1.41	1.28	−4.14	2.69	−1.45
HLA-A*11:01	2	0.53	0.18064	0.89	0.18	−1.63	1.06	−0.57
HLA-B*58:01	2	0.55	0.18064	1.36	1.06	−3.33	2.42	−0.9
HLA-B*57:01	2	0.56	0.18064	1.36	1.07	−3.39	2.43	−0.95
HLA-B*51:01	2	0.65	0.18064	1.41	1.28	−4.36	2.69	−1.67
HLA-B*07:02	2	0.72	0.18064	1.41	1.19	−3.75	2.6	−1.15
HLA-A*30:01	2	0.73	0.18424	1.41	1.28	−3.73	2.69	−1.05
HLA-A*68:02	2	1.4	0.18064	1.39	0.39	−3.11	1.78	−1.33
HLA-B*44:03	2	1.6	0.18424	1.41	1.28	−4.01	2.69	−1.33
HLA-B*44:02	2	1.9	0.18424	1.41	1.28	−4.16	2.69	−1.47
HLA-A*68:01	2	2.4	0.18064	0.76	0.68	−2.33	1.43	−0.9
HLA-B*40:01	2	3.1	0.18048	1.41	1.28	−4.44	2.69	−1.75

Notes:

1. MHC-I binding score was between 0 and 2. < 0.5 strong binder, 0.5-2 weak binder, > 2 non-binder.

2. The high Immunogenicity score means the degree of the peptide conformity to sequence preference was good.

3. The higher the TAP total score, the higher the likelihood that the peptide will be presented after being swallowed by DCs.