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. 2022 Feb 28;44(1):368–380. doi: 10.1080/0886022X.2022.2039195

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — MiR-142-5p was downregulated in cisplatin-induced kidney tissues. (A) MicroRNA expression, as determined by microarray analysis after cisplatin-induced kidney injury in mice; (B) MA plot showing 42 microRNAs with significantly increased changes in expression and 24 microRNAs with significantly decreased changes in expression following cisplatin treatment; (C) PCR analysis for the detection of the fold-change of miR-142-5p from cisplatin-treated mouse kidneys; (D) FISH analysis of miR-142-5p during cisplatin treatment of HK-2 cells. Data were expressed as mean ± SD (n = 3); *p < 0.05 versus control.