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. 2022 Feb 28;44(1):368–380. doi: 10.1080/0886022X.2022.2039195

Figure 6.

Figure 6.

P53 inhibition attenuated cisplatin-induced acute kidney injury by upregulating microRNA-142-5p. (A) Typical apoptotic nucleus in cells, as revealed by Hoechst staining; (B) apoptotic ratio of renal tubular cells; (C) apoptotic nucleus in cells, as revealed by TUNEL staining; (D) apoptotic ratio of renal tubulacells; (E) detection of miR‐142‐5p expression by RT-PCR in AKI mice; (F) Detection of miR‐142‐5p expression by RT-PCR in HK-2 cells. Data were expressed as mean ± SD (n = 3); *p < 0.05 versus control, #p < 0.05 versus cisplatin.