Table 3. Bacteria communities with differential abundance among groups categorized by their putative roles in the literature.
Bacteria | AB control group# | A-SCI group# | L-SCI group# | A-SCI vs AB* | L-SCI vs AB* | A-SCI vs L-SCI* |
---|---|---|---|---|---|---|
SCI Animal Model6 | ||||||
O_clostridiales | 29.7% | 33.7% | 52.9% | L-SCI > AB | ||
Metabolic Health 27–30 | ||||||
F_Acidaminococcaceae | 0.3% | 2.0% | 0.8% | A-SCI > AB | L-SCI > AB | |
F_Acidaminococcaceae; G_Phascolarctobacterium | 0.1% | 1.1% | 0.5% | A-SCI > AB | L-SCI > AB | |
F_lachnospiraceae | 14.9% | 17.2% | 35.7% | L-SCI > AB | ||
Antibiotics Use 31,32 | ||||||
F_Erysipelotrichaceae | 0.4% | 1.1% | 0.8% | A-SCI > AB | L-SCI > AB | |
F_Lachnospiraceae; G_Lachnoclostridium | 0.5% | 4.1% | 1.7% | A-SCI > AB | L-SCI > AB | |
Intestinal Inflammation32,35 | ||||||
F_Erysipelotrichaceae | 0.4% | 1.1% | 0.8% | A-SCI > AB | L-SCI > AB | |
F_Burkholderiaceae; G_Sutterella | 0.1% | 1.9% | 0.2% | A-SCI > AB | A-SCI > L-SCI | |
Depressive Disorders33,34 | ||||||
F_Rikenellaceae; G_Alistipes | 0.4% | 4.3% | 2.1% | A-SCI > AB | L-SCI > AB | |
F_Ruminococcaceae; G_Oscillibacter | 0.1% | 0.5% | 0.4% | A-SCI > AB | L-SCI > AB | |
Physical Activity36 | ||||||
F_Burkholderiaceae | 3.6% | 2.1% | 0.6% | L-SCI < AB | A-SCI > L-SCI | |
Roles Unknown in Literature | ||||||
F_Desulfovibrionaceae | 0.1% | 1.1% | 0.5% | A-SCI > AB | ||
G_Eggerthellaceae | 0.0% | 0.0% | 0.1% | L-SCI > AB | ||
F_Marinifilaceae | 0.1% | 1.5% | 0.2% | A-SCI > AB | A-SCI > L-SCI | |
F_Marinifilaceae; G_Odoribacter | 0.1% | 1.3% | 0.2% | A-SCI > AB | A-SCI > L-SCI | |
F_Campylobacteraceae; G_Campylobacter | 0.2% | 0.0% | 0.0% | L-SCI < AB | ||
O_Bacillales | 0.7% | 0.1% | 0.1% | L-SCI < AB | ||
F_Lachnospiraceae; G_Eisenbergiella | 0.0% | 1.3% | 0.7% | A-SCI > AB | L-SCI > AB | |
F_Ruminococcaceae; G_Eubacterium coprostanoligenes group; S_unidentified | 0.0% | 0.7% | 0.7% | A-SCI > AB | L-SCI > AB | |
F_Ruminococcaceae; G_Anaerotruncus | 0.0% | 0.0% | 0.2% | A-SCI > AB | L-SCI > AB | |
F_Acidaminococcaceae; G_Phascolarctobacterium | 0.1% | 1.1% | 0.5% | A-SCI > AB | L-SCI > AB | |
F_Erysipelotrichaceae; G_Erysipelatoclostridium | 0.0% | 0.2% | 0.0% | A-SCI > AB |
#AB, able-bodied; A-SCI, acute spinal cord injury; L-SCI, long-standing spinal cord injury;
*Significantly different groups