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. 2022 Jan 30;14(1):e21749. doi: 10.7759/cureus.21749

Table 3. Association of vitamin D levels with distal radius fracture post-stratification of various participants’ characteristics.

Participants' characteristics Vit D levels Distal Radius Fracture Total p-value
Yes No
n (%) n (%)
Gender
Male Severe deficiency 6(16.7) 5(14.7) 11(15.7) 0.116ꬸ
Normal 27(75) 19(55.9) 46(65.7)
Mild to moderate deficiency 3(8.3) 9(26.5) 12(17.1)
Toxicity 0(0) 1(2.9) 1(1.4)
Total 36(100) 34(100) 70(100)
Female Severe deficiency 11(37.9) 11(35.5) 22(36.7) 0.032*ꬸ
Normal 16(55.2) 10(32.3) 26(43.3)
Mild to moderate deficiency 1(3.4) 9(29)b 10(16.7)
Toxicity 1(3.4) 1(3.2) 2(3.3)
Total 29(100) 31(100) 60(100)
Age in years
≤41 Severe deficiency 9(30) 9(24.3) 18(26.9) 0.012*ꬸ
Normal 21(70) 18(48.6) 39(58.2)
Mild to moderate deficiency 0(0) 8(21.6)b 8(11.9)
Toxicity 0(0) 2(5.4) 2(3)
Total 30(100) 37(100) 67(100)
>41 Severe deficiency 8(22.9) 7(25) 15(23.8) 0.067ꬸ
Normal 22(62.9) 11(39.3) 33(52.4)
Mild to moderate deficiency 4(11.4) 10(35.7) 14(22.2)
Toxicity 1(2.9) 0(0) 1(1.6)
Total 35(100) 28(100) 63(100)
BMI category
≤25 Severe deficiency 9(29) 4(13.8) 13(21.7) 0.003*ꬸ
Normal 21(67.7) 15(51.7) 36(60)
Mild to moderate deficiency 0(0) 9(31)b 9(15)
Toxicity 1(3.2) 1(3.4) 2(3.3)
Total 31(100) 29(100) 60(100)
>25 Severe deficiency 8(23.5) 12(33.3) 20(28.6) 0.112ꬸ
Normal 22(64.7) 14(38.9) 36(51.4)
Mild to moderate deficiency 4(11.8) 9(25) 13(18.6)
Toxicity 0(0) 1(2.8) 1(1.4)
Total 34(100) 36(100) 70(100)
Menopause (for females)
No Severe deficiency 9(42.9) 8(34.8) 17(38.6) 0.014*ꬸ
Normal 12(57.1) 7(30.4) 19(43.2)
Mild to moderate deficiency 0(0) 7(30.4)B 7(15.9)
Toxicity 0(0) 1(4.3) 1(2.3)
Total 21(100) 23(100) 44(100)
Yes Severe deficiency 2(25) 3(37.5) 5(31.3) 1.000ꬸ
Normal 4(50) 3(37.5) 7(43.8)
Mild to moderate deficiency 1(12.5) 2(25) 3(18.8)
Toxicity 1(12.5) 0(0) 1(6.3)
Total 8(100) 8(100) 16(100)
Sun exposure in hours
≤1 hour Severe deficiency 10(26.3) 12(29.3) 22(27.8) 0.316ꬸ
Normal 23(60.5) 18(43.9) 41(51.9)
Mild to moderate deficiency 4(10.5) 10(24.4) 14(17.7)
Toxicity 1(2.6) 1(2.4) 2(2.5)
Total 38(100) 41(100) 79(100)
> 1 hour Severe deficiency 7(25.9) 4(16.7) 11(21.6) 0.003*ꬸ
Normal 20(74.1) 11(45.8)b 31(60.8)
Mild to moderate deficiency 0(0) 8(33.3)b 8(15.7)
Toxicity 0(0) 1(4.2) 1(2)
Total 27(100) 24(100) 51(100)
Albumin
≤4.2 Severe deficiency 9(28.1) 12(30.8) 21(29.6) 0.253ꬸ
Normal 19(59.4) 16(41) 35(49.3)
Mild to moderate deficiency 3(9.4) 10(25.6) 13(18.3)
Toxicity 1(3.1) 1(2.6) 2(2.8)
Total 32(100) 39(100) 71(100)
>4.2 Severe deficiency 8(24.2) 4(15.4) 12(20.3) 0.010*ꬸ
Normal 24(72.7) 13(50) 37(62.7)
Mild to moderate deficiency 1(3) 8(30.8)b 9(15.3)
Toxicity 0(0) 1(3.8) 1(1.7)
Total 33(100) 26(100) 59(100)
Calcium level
≤9.2 Severe deficiency 10(32.3) 11(28.9) 21(30.4) 0.106ꬸ
Normal 18(58.1) 17(44.7) 35(50.7)
Mild to moderate deficiency 2(6.5) 10(26.3) 12(17.4)
Toxicity 1(3.2) 0(0) 1(1.4)
Total 31(100) 38(100) 69(100)
>9.2 Severe deficiency 7(20.6) 5(18.5) 12(19.7) 0.016*ꬸ
Normal 25(73.5) 12(44.4)b 37(60.7)
Mild to moderate deficiency 2(5.9) 8(29.6)b 10(16.4)
Toxicity 0(0) 2(7.4) 2(3.3)
Total 34(100) 27(100) 61(100)
Alkaline phosphate level
≤9.1 Severe deficiency 7(21.2) 8(24.2) 15(22.7) 0.172ꬸ
Normal 24(72.7) 18(54.5) 42(63.6)
Mild to moderate deficiency 1(3) 6(18.2) 7(10.6)
Toxicity 1(3) 1(3) 2(3)
Total 33(100) 33(100) 66(100)
>9.1 Severe deficiency 10(31.3) 8(25) 18(28.1) 0.020*ꬸ
Normal 19(59.4) 11(34.4)b 30(46.9)
Mild to moderate deficiency 3(9.4) 12(37.5)b 15(23.4)
Toxicity 0(0) 1(3.1) 1(1.6)
Total 32(100) 32(100) 64(100)
Smoking Status
Smoker Normal 7(77.8) 4(57.1) 11(68.8) 0.758ꬸ
Mild to moderate deficiency 2(22.2) 2(28.6) 4(25)
Toxicity 0(0) 1(14.3) 1(6.3)
Total 9(100) 7(100) 16(100)
Occasional Smoker Severe deficiency 2(25) 1(25) 3(25) 1.000ꬸ
Normal 6(75) 3(75) 9(75)
Total 8(100) 4(100) 12(100)
No Smoker Severe deficiency 15(31.3) 15(27.8) 30(29.4) 0.003*ꬸ
Normal 30(62.5) 22(40.7)b 52(51)
Mild to moderate deficiency 2(4.2) 16(29.6)b 18(17.6)
Toxicity 1(2.1) 1(1.9) 2(2)
Total 48(100) 54(100) 102(100)
Comorbidity
No Severe deficiency 11(23.4) 7(20.6) 18(22.2) 0.007*ꬸ
Normal 35(74.5) 18(52.9)b 53(65.4)
Mild to moderate deficiency 1(2.1) 8(23.5)b 9(11.1)
Toxicity 0(0) 1(2.9) 1(1.2)
Total 47(100) 34(100) 81(100)
Yes Severe deficiency 6(33.3) 9(29) 15(30.6) 0.629ꬸ
Normal 8(44.4) 11(35.5) 19(38.8)
Mild to moderate deficiency 3(16.7) 10(32.3) 13(26.5)
Toxicity 1(5.6) 1(3.2) 2(4.1)
Total 18(100) 31(100) 49(100)
P<0.05, ꬸ Fisher's exact