TABLE 2.
Concentrations of N-nitrosamines, nitrate, and nitrite in saliva of control and schistosomiasis patientsa
| Parameter | Concnb in group infected with:
|
||
|---|---|---|---|
| Uninfected control | S. mansonic | S. haematobiumc | |
| N-Nitrosamine concn (μg/day) | |||
| NDMAd | 0.27 ± 0.47 [11/27] | 2.9 ± 2.9 [64/65] (P < 0.001) | 19.2 ± 21 [79/79] (P < 0.001) |
| NPIPd | 0.6 [1/27] | 0.4 ± 0.3 [40/65] | 1.6 ± 2.3 [56/79] (P < 0.001) |
| NPYRd | 0.7 [1/27] | 0.9 ± 0.9 [59/65] | 1.3 ± 1.9 [58/79] (P < 0.1] |
| Nitrate concn in saliva (ppm) | 41 ± 52 [27/27] | 60 ± 59 [61/64] | 52 ± 48 [120/129] |
| Nitrate concn in urine (mg/day) | 139 ± 82 [27/27] | 249 ± 12 [65/65] (P < 0.001) | 174 ± 176 [77/79] (P < 0.005) |
| Nitrite concn in saliva (ppm) | 8.8 ± 9.0 [27/27] | 7.8 ± 9.5 [61/64] | 7.5 ± 7.9 [120/129] |
| Nitrite concn in urine (mg/day) | 1.7 ± 0.3 [2/27] | 3.2 ± 13 [5/65] | 7.9 ± 24 [18/79] |
a
Reprinted from reference 161 with permission of the publisher.
b
Values are mean ± SD of individual samples [number of positive samples/total number assayed].
c
Comparison between the control group, S. mansoni-infected patients, and S. haematobium-infected patients by the Wilcoxon rank sum test.
d
Volatile nitrosamines: NDMA, N-nitrosodimethylamine; NPIP, N-nitrosopiperidine; NPR, N-nitrosopyrrolidine.