TABLE 3.

Changes in carcinogen-metabolizing enzyme activities after infection of male mice for different periods with 100 to 120 cercariae of S. mansoni

Enzyme	Enzyme activity (% of control)a after infection for (days):
	20	30	45	60	75
Cytochrome P-450b	+81	+161	−37	−49	−58
Cytochrome b5b	+89	+49	NS	−38	−46
NADPH-cytochrome c reductaseb	+61	NS	−46	−30	−26
Arylhydrocarbon hydroxylaseb	+64	+92	−37	−48	−47
NDMA-N-demethylase Ic	+39	+64	+35	NS
NDMA-N-demethylase IIc	+172	+162	+171	+175
Glutathioned	NS	NS	−18	−31	−27
Glutathione S-transferased	NS	NS	+45	NS	−30
Glutathione reductased	+34	−39	NS	+35	+79

^aThe changes in activity are presented as activation (+), inhibition (−), or not significantly different from control (NS). 

^bData are from reference 200. 

^cData are from reference 157. 

^dData are from reference 199a.