Table 1.
Characteristics of research subjects.
| Variable | METS-IR categories | ||||
|---|---|---|---|---|---|
| Q1 (18.88-27.66) | Q2 (27.66-30.93) | Q3 (30.94-34.33) | Q4 (34.33-67.05) | P value | |
| N | 2683 | 2682 | 2682 | 2683 | |
| Age (years) | 42.62 ± 15.14 | 43.40 ± 15.01 | 44.01 ± 15.03 | 44.56 ± 15.34 | <0.001 |
| Sex | <0.001 | ||||
| Women | 1331 (49.61%) | 1225 (45.67%) | 1172 (43.70%) | 1111 (41.41%) | |
| Men | 1352 (50.39%) | 1457 (54.33%) | 1510 (56.30%) | 1572 (58.59%) | |
| BMI (kg/m2) | 19.17 ± 1.31 | 21.24 ± 1.18 | 22.58 ± 1.21 | 23.53 ± 1.08 | <0.001 |
| SBP (mmHg) | 114.72 ± 15.61 | 121.26 ± 16.30 | 125.84 ± 15.92 | 129.73 ± 16.62 | <0.001 |
| DBP (mmHg) | 69.56 ± 9.33 | 72.83 ± 9.91 | 75.24 ± 10.10 | 77.77 ± 10.24 | <0.001 |
| TC (mmol/L) | 4.57 ± 0.73 | 4.61 ± 0.74 | 4.66 ± 0.70 | 4.64 ± 0.81 | <0.001 |
| TG (mmol/L) | 0.83 (0.68-1.05) | 1.03 (0.82-1.30) | 1.26 (0.99-1.61) | 1.87 (1.38-2.55) | <0.001 |
| HDL-C (mmol/L) | 1.76 ± 0.33 | 1.56 ± 0.30 | 1.38 ± 0.25 | 1.12 ± 0.20 | <0.001 |
| FPG (mmol/L) | 4.97 ± 0.48 | 5.14 ± 0.64 | 5.25 ± 0.82 | 5.51 ± 1.15 | <0.001 |
| LDL-C (mmol/L) | 2.13 ± 0.46 | 2.27 ± 0.47 | 2.37 ± 0.45 | 2.34 ± 0.46 | <0.001 |
| ALP (U/L) | 66.54 ± 24.70 | 71.24 ± 22.04 | 74.97 ± 21.85 | 77.26 ± 21.37 | <0.001 |
| GLB (g/L) | 29.12 ± 3.77 | 29.24 ± 3.94 | 29.32 ± 3.94 | 29.58 ± 4.23 | <0.001 |
| GGT (U/L) | 18.00 (14.00-23.00) | 20.00 (16.00-27.00) | 23.00 (18.00-33.00) | 29.00 (21.00-44.00) | <0.001 |
| ALB (g/L) | 44.54 ± 2.80 | 44.53 ± 2.84 | 44.50 ± 2.71 | 44.57 ± 2.73 | 0.856 |
| ALT (U/L) | 13.00 (11.00-18.00) | 15.00 (12.00-20.00) | 18.00 (13.00-24.00) | 21.00 (15.00-28.00) | <0.001 |
| AST (U/L) | 20.00 (17.00-23.00) | 21.00 (18.00-25.00) | 22.00 (19.00-26.00) | 23.00 (20.00-27.00) | <0.001 |
| TP (g/L) | 73.66 ± 4.23 | 73.77 ± 4.17 | 73.82 ± 4.19 | 74.15 ± 4.41 | <0.001 |
| BUN (mmol/L) | 4.39 ± 1.41 | 4.64 ± 1.45 | 4.77 ± 1.35 | 4.80 ± 1.49 | <0.001 |
| Cr (μmol/L) | 77.13 ± 21.49 | 83.21 ± 26.57 | 86.89 ± 21.95 | 91.02 ± 35.05 | <0.001 |
| UA (mmol/L) | 247.34 ± 79.22 | 282.93 ± 84.85 | 313.48 ± 82.12 | 341.57 ± 82.96 | <0.001 |
Variables are presented as the mean ± SD or n (%) or median (Q1, Q3). Abbreviations: METS-IR: metabolic score for insulin resistance; SBP: systolic blood pressure; BMI: body mass index; DBP: diastolic blood pressure; TC: total cholesterol; FPG: fasting plasma glucose; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; AST: aspartate aminotransferase; TP: total protein; ALP: alkaline phosphatase; GLB: globulin; ALB: albumin; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; NAFLD: nonalcoholic fatty liver disease.