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(A) Effects of MET and MK571 on 5-CF level. (B) Mean fluorescence intensity (MFI) in each group. Data are expressed as means ± SD. MRP1, multidrug resistance protein 1; MET, metformin; 5-CF, 5-carboxyfluorescein; CSE, cigarette smoke extract; DEX, dexamethasone; 5-CFDA, 5-carboxyfluorescein diacetate. *p < 0.01 vs. control group; **p < 0.01 vs. 5-CFDA group; #p < 0.01 vs. CSE group; Δ p < 0.01 vs. DEX+MET group (n = 5).
