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. 2022 Mar 1;26(2):95–111. doi: 10.4196/kjpp.2022.26.2.95

Fig. 12. MK571 significantly reduced the expression of HDAC2 protein and mRNA induced by MET.

Fig. 12

(A) Effect of 20 μM MK571 on the expression of HDAC2 protein. (B) Quantitative analysis results of protein expression in each group. Data are expressed as means ± SD. *p < 0.01 vs. control group; #p < 0.01 vs. CSE group; Δp < 0.01 vs. DEX+MET group (n = 3). (C) Effect of MK571 on mRNA expression of HDAC2. Data are expressed as means ± SD. *p < 0.01 vs. control group; #p < 0.01 vs. CSE group; Δp < 0.01 vs. DEX+MET group (n = 5). (D) Effects of different concentrations of MK571 on the expression of HDAC2 protein. (E) Quantitative analysis results of protein expression in each group. Data are expressed as means ± SD. MET, metformin; HDAC2, histone deacetylase 2; CSE, cigarette smoke extract; DEX, dexamethasone. *p < 0.05 or #p < 0.01 vs. control group (n = 3).