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. 2022 Mar 3;20:102. doi: 10.1186/s12916-022-02312-5

Table 3.

RBD-ACE2 affinity measured by MST. All experiments were performed in titration in triplicates and analyzed by the MO Affinity Analysis software (NanoTemper) by Hill fit

RBD EC50 (nM) EC50 confidence (nM)
Wuhan strain 40.7 1.8
Beta 35.2 1.7
Delta 33.6 2.2
Omicron 42.3 1.6