Table 4.
Comparative analysis of PROKERALA, GIESSEN, ASPIRE PH and PAPUCO registries. PH = Pulmonary hypertension, PAH = Pulmonary arterial hypertension, PVH = Pulmonary venous hypertension, LD-PH = Lung disease associated pulmonary hypertension, CTEPH = Chronic thromboembolic pulmonary hypertension, Baseline FC = functional class, DC = dual combination drugs.
| PROKERALA registry | GIESSEN-PH registry | ASPIRE-PH registry | PAPUCO registry | |
|---|---|---|---|---|
| PH patients, n | 2003 | 2067 | 1344 | 209 |
| Female gender, % | 52 | 53.5 | 62 | 59 |
| Mean age, years | 56 | 61 | 59 | 48 |
| Type of PH, % | ||||
| PAH | 15.8 | 33.1 | 44.5 | 16 |
| PVH | 64.6 | 14.9 | 11.7 | 69 |
| LD-PH | 14.6 | 26.4 | 13.2 | 11 |
| CTEPH | 3.6 | 22.2 | 18 | 2 |
| Baseline FC, % | ||||
| II | 65.5 | 11.5 | 15 | 33 |
| III | 24.5 | 42.3 | 65 | 44 |
| IV | 4.8 | 17.9 | 16 | 22 |
| Treatment, % | ||||
| Monotherapy | 15.9 | 72 | 46 | 3 |
| DC | 1.8 | 15 | 8 | – |
| Survival at 1 year, % | 95.9 | 85.5 | 88 | 79 |