Table 1:
Baseline patient characteristics.
| Variables | n | Mean ± SD, n (%) |
|---|---|---|
| Age at RHC, years | 80 | 54.4±10.2 |
| Age at liver disease diagnosis, years | 70 | 47.3±13.3 |
| Female gender | 87 | 47(54.0) |
| Race | 80 | |
| White | 67(84.8) | |
| African American | 8(10.1) | |
| Other | 4(5.1) | |
| BMI, kg/m 2 | 75 | 31.6±6.4 |
| Etiology of liver disease | 80 | |
| • Alcohol related | 15(18.7) | |
| • Hepatitis C | 16(20) | |
| • Alcohol and Hepatitis C both | 10(12.5) | |
| • NAFLD | 16(20) | |
| • Others | 23(28.7) | |
| CTP score | 78 | 8.1±2.0 |
| INR | 78 | 1.2±0.20 |
| Total bilirubin, mg/dl | 78 | 2.6±1.8 |
| Serum sodium, mmol/dl | 78 | 138.6±4.1 |
| Serum Creatinine, mg/dl | 78 | 1.3±0.58 |
| MELD | 78 | 13.2±4.4 |
| MELD-NA | 78 | 14.1±5.3 |
| Serum Aspartate Aminotransferase, U/L | 78 | 56.9±39.4 |
| Serum Alanine Aminotransferase, U/L | 77 | 32.5±28.5 |
| Serum Alkaline Phosphatase, U/L | 78 | 144.2±91.6 |
| Albumin, g/dl | 78 | 3.3±0.62 |
| Ascites | 79 | |
| Absent | 32(40.5) | |
| Present | 47(59.5) | |
| Hepatic encephalopathy | 79 | |
| Absent | 39(49.4) | |
| Present | 40(50.6) | |
| TIPS | 76 | 14(18.4) |
| WHO class | 77 | |
| I | 8(10.4) | |
| II | 25(32.5) | |
| III | 40(51.9) | |
| IV | 4(5.2) | |
| Distance walked in 6MWT, m | 58 | 328±115 |
| LVEF, % | 75 | 59.7±5.2 |
| RVSP, mmHg | 71 | 67.1±20.1 |
| Right Ventricular function (echocardiography) | 75 | |
| normal | 36 (48) | |
| abnormal | 39 (52) |
BMI, Body Mass Index; CTP, Child-Turcotte-Pugh; INR, International Normalized Ratio; LVEF, Left Ventricular Ejection Fraction, Model for End stage Liver Disease; MELD- Na, Model for End stage Liver Disease with serum sodium; NAFLD, Non-alcoholic Fatty liver disease; WHO, New York Heart Association; RHC, Right Heart Catheterization; RVSP, Right Ventricle systolic Pressure; TIPS; Transjugular Intrahepatic Portosystemic Shunt.