Table 2.

Associations of Actigraphy-Based Sleep Duration with ILA

Sleep Duration	No. Participants	Odds Ratio for ILA (95% CI) per 1-hour increment	P-value	P-value for Interaction
Model 1
Less than 6 hours*	199	1.54 (1.02 to 2.32)	0.04
6 to 8 hours	625	0.74 (0.47 to 1.15)	0.18
Greater than 8 hours	287	2.21 (1.36 to 3.58)	0.001
Model 2
Less than 6 hours*	199	1.13 (0.66 to 1.92)	0.66
6 to 8 hours	625	0.70 (0.42 to 1.15)	0.18
Greater than 8 hours	287	2.66 (1.42 to 4.99)	0.002
	Stratified Analysis
Fragmentation Index
Less than 6 hours				0.34
Tertile 1	53	1.64 (0.58 to 4.62)	0.35
Tertile 2	72	0.92 (0.27 to 3.09)	0.79
Tertile 3	74	0.56 (0.22 to 1.44)	0.29
6 to 8 hours				0.06
Tertile 1	206	0.46 (0.17 to 1.22)	0.12
Tertile 2	214	0.43 (0.19 to 0.97)	0.04
Tertile 3	205	1.61 (0.67 to 3.89)	0.29
Greater than 8 hours				0.52
Tertile 1	111	4.63 (1.47 to 14.54)	0.01
Tertile 2	85	2.30 (0.98 to 5.42)	0.06
Tertile 3	91	2.05 (0.56 to 7.59)	0.28
Chronotype
Less than 6 hours				0.91
Non-evening	182	0.85 (0.50 to 1.46)	0.56
Evening	17	1.90 (0.05 to 67.00)	0.72
6 to 8 hours				0.80
Non-evening	571	0.69 (0.41 to 1.18)	0.17
Evening	54	0.87 (0.17 to 4.43)	0.87
Greater than 8 hours				0.70
Non-evening	269	2.64 (1.37 to 5.07)	0.004
Evening	18	4.46 (0.27 to 74.87)	0.30
Sleep Midpoint
Less than 6 hours				0.64
Before 5:00 AM	148	0.96 (0.50 to 1.85)	0.91
After 5:00 AM	51	0.49 (0.13 to 1.82)	0.28
6 to 8 hours				0.97
Before 5:00 AM	557	0.70 (0.40 to 1.20)	0.19
After 5:00 AM	68	0.81 (0.24 to 2.72)	0.74
Greater than 8 hours				0.02
Before 5:00 AM	268	3.71 (1.80 to 7.63)	<0.001
After 5:00 AM	19	0.38 (0.03 to 4.90)	0.46

Model 1: Unadjusted

Model 2: Adjusted for age, sex, race/ethnicity, smoking status, cigarette pack-years, body mass index, percent emphysema, systolic and diastolic blood pressures, statin use, apnea-hypopnea index, total intentional exercise, education attainment, diabetes, antidepressant use.

^*Results are reported per 1-hour decrement in sleep duration