Effect of 3D Registration on Mean Symmetric Surface Distance (MSD) Between Manually Drawn Contours of End-Systolic and End-Diastolic Cardiac MRI. The Table Compares the SynthMorph (sm-Shapes) and VoxelMorph (vm-ncc) Models Performing Best At This Task Despite Optimization for Brain Registration, Without Retraining. A Reduction in MSD Translates to Better Alignment of the Left Ventricular Structures. SD Abbreviates Standard Deviation, and We Highlight the Best Result for Each Set of Contours in Bold