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. Author manuscript; available in PMC: 2022 Mar 3.
Published in final edited form as: IEEE Trans Med Imaging. 2022 Mar 2;41(3):543–558. doi: 10.1109/TMI.2021.3116879

TABLE III.

Effect of 3D Registration on Mean Symmetric Surface Distance (MSD) Between Manually Drawn Contours of End-Systolic and End-Diastolic Cardiac MRI. The Table Compares the SynthMorph (sm-Shapes) and VoxelMorph (vm-ncc) Models Performing Best At This Task Despite Optimization for Brain Registration, Without Retraining. A Reduction in MSD Translates to Better Alignment of the Left Ventricular Structures. SD Abbreviates Standard Deviation, and We Highlight the Best Result for Each Set of Contours in Bold

Endocardium Epicardium
SynthMorph VoxelMorph SynthMorph VoxelMorph
Pairs improved 29/33 (88%) 28/33 (85%) 28/33 (85%) 25/33 (76%)
Mean ± SD (mm) 0.8 ± 0.1 −0.7 ± 0.1 0.6 ± 0.1 −0.2 ± 0.1
Mean ± SD (%) 10.2 ± 1.6 −9.0 ± 1.9 11.6 ± 1.5 −4.3 ± 1.4
Best pair (%) 35.4 −33.8 29.6 −22.5
Worst pair (%) +3.9 +6.1 +6.0 +13.2