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. Author manuscript; available in PMC: 2022 Mar 3.
Published in final edited form as: Nat Chem Biol. 2021 Dec 16;18(3):313–320. doi: 10.1038/s41589-021-00914-3

Fig. 5. Membrane binding of E-Syt1 C2CD and C2E differentially depends upon PI(4,5)P2 and DOPS.

Fig. 5.

(a) Extension-time trajectories of E-Syt1 C2ABCDE at constant force with 10 mol% PI(4,5)P2. (b) Force-dependent probabilities and transition rates of different E-Syt1 binding states (symbols) and their best model fits (lines). (c) Extension-time trajectory of E-Syt1 C2ABCDE at constant force in the presence of 30% DOPS and no PI(4,5)P2.