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. 2022 Feb 17;10:805402. doi: 10.3389/fcell.2022.805402

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Copyright © 2022 Jianfeng, Yutao and Jianbin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of weighted gene co-expression network analysis in TCGA-PRAD. (A) A hierarchical cluster tree was constructed, with each leaf representing a gene and each branch representing a co-expression module. A total of eight co-expression modules were generated. (B) Correlation coefficients between different factors and co-expression modules, where the brown (COR = 0.83; p < 0.001), gray (COR = 0.45; p < 0.001), and pink modules (COR = 0.42; p < 0.001) had a positive correlation with INMT, and the green module (COR = -0.22; p < 0.001) had a negative correlation with INMT. (C) The pathway enrichment analysis of the INMT co-expression genes in the green module. (D) The KEGG pathway annotation and enrichment analysis of the INMT co-expression genes in the green module.