Table 1.

Background Information of the Human Donors Used for the Generation of Precision-Cut Lung Slices

Donor no.	Sex	Age, years	Lung lobe	Weight, length × width × height	Diagnostic finding	Smoker status	Methods and analysis	Processing	Chemotherapy or radiotherapy
1	Male	71	LL, right	29 g, 13 × 4.5 × 2 cm	Filiae of a non–small cell carcinoma with low differentiation after bladder cancer	No smoking	WST-1 and LDH assay, cilia check, histologic evaluation, RNA sequencing	Immediate	No
2	Male	55	UL, left	7 × 3 × 3.5 cm	NSCLC after anaplastic thyroid cancer	60 py until 6 years before surgery	WST-1 and LDH assay, cilia check, histologic evaluation	Immediate	Radioiodo-therapy
3	Female	71	UL, left	155 g, 15 × 10 × 3 cm	Squamous cell carcinoma with low cornification and low differentiation	20 py until 6 years before surgery	WST-1 and LDH assays, cilia check, histologic evaluation	Immediately filled, then stored overnight at 4°C, before further processed	No
4	Female	75	LL, left	30 g, 10 × 6 × 3 cm	Adenocarcinoma	Until 16 years before surgery	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate	No
5	Female	76	UL, left	18 × 12 × 6 cm	NSCLC, adenocarcinoma	No smoking	WST-1 and LDH assays, cilia check, histologic evaluation	Immediately filled, then stored overnight at 4°C, before further processed	No
6	Male	69	UL, right	131 g, 14 × 8.5 × 3 cm	Adenocarcinoma	75 py	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate	No
7	Male	68	UL, left	589 g, 24 × 15 × 7 cm	NSCLC, adenocarcinoma with low differentiation	No smoking	WST-1 and LDH assays, cilia check, histologic evaluation, RNA sequencing	Immediate	No
8	Male	57	LL, left	493 g, 18 × 13.5 × 4.6 cm	Invasive adenocarcinoma	20 py	WST-1 and LDH assays, cilia check, histologic evaluation, RNA sequencing	Immediate	No
9	Male	58	UL, right	300 g, 19 × 15 × 3.5 cm	Squamous cell carcinoma with cornification	110 py	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate	No
10	Female	62	LL, ML, right	565 g, 22 × 12 × 4.5 cm	Fibrosis, sarcoidosis	15 py until 19 years before surgery	Histologic evaluation	Immediately filled, then stored overnight at 4°C, before further processed
11	Female	55	UL, LL, right	498 g, 19.5 × 12 × 6 cm	Fibrosis, UIP pattern, IPF	No smoking	WST-1 and LDH assays, cilia check, histologic evaluation	Tissue stored overnight at 4°C, then processed
12	Female	50	UL, LL, right	432 g, 21 × 13.5 × 4 cm	Fibrosis, UIP-pattern, antisynthetase Syndrome	20 py until 3 years before surgery	WST-1 and LDH assay, cilia check, histologic evaluation	Tissue stored overnight at 4°C, then processed
13	Male	59	UL, LL, right	585 g, 22 × 18 × 7 cm	Fibrosis, clinical NSIP	2 py until 37 years before surgery	WST-1 and LDH assay, cilia checks, histologic evaluation	Tissue stored overnight at 4°C, then processed
14	Male	62	UL, right	556 g, 18.5 × 14 × 3.5 cm	Fibrosis, chronic interstitial pneumonia, UIP pattern	22 py until 22 years before surgery	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate
15	Male	34	UL, LL, right	582 g, 22.5 × 14.5 × 5 cm	Fibrosis, IPF	No smoking	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate
16	Female	50	UL, ML, right	389 g, 20 × 12.5 × 3 cm	Fibrosis, UIP pattern, ANCA-positive interstitial pneumonia	No smoking	WST-1 and LDH assays, cilia check, histologic evaluation	Immediate

ANCA, antineutrophil cytoplasm autoantibodies; IPF, idiopathic pulmonary fibrosis; LDH, lactate dehydrogenase; LL, lower lobe; ML, middle lobe; NSCLC, non–small cell lung cancer; NSIP, nonspecific interstitial pneumonia; py, pack-years; UIP, usual interstitial pneumonia; UL, upper lobe; WST-1, water soluble tetrazolium 1.