TABLE 2.
Results of proton magnetic resonance spectroscopy in the hypothalamus of the entire cohort1
| Ratios | Eutrophic,2n = 37 | Obese,3n = 37 | P value |
|---|---|---|---|
| Glu/Cr | 1.05 (± 0.17) | 1.03 (± 0.32) | 0.85 |
| Glx/Cr | 1.73 (± 0.36) | 1.78 (± 0.41) | 0.59 |
| NAA/Cr | 0.84 (± 0.20) | 0.70 (± 0.19) | 0.004 |
| mI/Cr | 0.96 (± 0.18) | 0.99 (± 0.16) | 0.49 |
| GPC + PCh/Cr | 0.34 (± 0.04) | 0.33 (± 0.03) | 0.19 |
1
Data presented as Mean (± SD). Significance between the groups was tested using Unpaired T test. Cr, creatine; Glu, glutamate; Glx, sum of glutamate and glutamine; GPC, glycerophosphocholine; mI, myo-inositol; NAA, N-acetylaspartate; PCh, phosphocholine.
2
Eutrophic participants presented BMI z-scores ≤ 1.
3
Obese patients presented BMI z-scores ≥ 2.