TABLE 3.
Serum protein levels and NAA/Cr ratio correlations within the entire cohort1
| NAA/Cr | rho | P value | |
|---|---|---|---|
| r | |||
| Serum hormones | |||
| Insulin | — | −0.27 | 0.04 |
| Leptin | — | −0.07 | 0.61 |
| C-peptide | — | −0.26 | 0.04 |
| Amylin | −0.27 | — | 0.04 |
| Glucagon | — | −0.19 | 0.15 |
| GLP-1 | −0.11 | — | 0.43 |
| GIP | — | −0.12 | 0.36 |
| Ghrelin | — | −0.30 | 0.02 |
| Serum neuropeptides | |||
| α-MSH | — | 0.26 | 0.08 |
| β-Endorphin | — | 0.18 | 0.22 |
| Neurotensin | — | 0.16 | 0.24 |
| Oxytocin | — | 0.13 | 0.36 |
| Orexin | — | 0.13 | 0.36 |
| MCH | — | 0.04 | 0.75 |
| NPY | −0.27 | — | 0.04 |
| Serum cytokines | |||
| L1β | — | 0.07 | 0.59 |
| IL-6 | — | 0.08 | 0.57 |
| IL-8 | — | 0.26 | 0.04 |
| IL-10 | — | 0.06 | 0.66 |
1
Significant differences were tested using Pearson coefficients (r) or nonparametric Spearman correlation (rho) within the entire cohort [eutrophic (n = 37) and obese (n = 37)]. α-MSH, α-melanocyte-stimulating hormone; Cr, creatine; GIP, gastric inhibitory polypeptide; GLP-1, glucagon-like peptide-1; MCH, melanin-concentrating hormone; NAA, N-acetylaspartate; NPY, neuropeptide Y.