Table 2.
Role of microtubule dysfunction on neurodevelopment
| Research papers | Target studied | Main effects evidenced |
|---|---|---|
| Franker and Hoogenraad (2013), Huang et al. (2012), Liu and Dwyer (2014) | MAP | Axon formation and navigation |
| Augustyniak et al. (2017) | MAP 2 | Mitochondrial biogenesis |
| Poulain and Sobel (2007) | Stathmin 2 | Neuritogenesis, axonogenesis and dendritogenesis |
| de Nijs et al. (2006) | EFHC1 | Altered cell division and juvenile myoclonic epilepsy |
| Xia et al. (2003), Nakajima et al. (2012) | KIF5A | Alteration on GABA A functioning and predisposition to seizures |