Fig. 5.

a–c A neonate with SEDC. Radiographs show a broad thorax and modest platyspondyly (flattening of the vertebral bodies) due to delayed vertebral ossification. The delayed ossification is prominent in the dorsal vertebral bodies, giving rise to pear-shaped vertebral bodies seen on the lateral view. The delayed ossification is more severe in the cervical spine and sacrum than in the thoracolumbar spine, creating anisospondyly (increased variability of the size of the vertebral bodies). The ilia are craniocaudally short, the pubic bones are absent, epiphyseal ossification of the distal femora is retarded (typically seen by 39 weeks of gestation), and the long bones show mild metaphyseal widening