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. 2021 Oct 31;61(3):387–400. doi: 10.1007/s40262-021-01071-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Pharmacokinetic model of intravenously administered inebilizumab. CL clearance, K_dec first-order rate constant describing the decrease of V_max over time, K_m concentration to achieve half of V_max, Q intercompartmental clearance, V_c volume of distribution in the central compartment, V_max maximum velocity of Michaelis–Menten equation, V_p volume of distribution in the peripheral compartment