Table 2.

Effect of chronic exposure to a plateau hypoxic environment on oxidative stress parameters in the hippocampus and the cortex of H and P group rats

	Hippocampus			Cortex
	H	P	P value	H	P	P value
MDA (nmol/mg prot)	0.13 ± 0.02	0.10 ± 0.01	0.033	0.15 ± 0.02	0.11 ± 0.01	0.019
SOD (U/mg prot)	0.86 ± 0.13	1.10 ± 0.06	0.026	0.49 ± 0.09	0.85 ± 0.16	0.013
CAT (nmol/min/mg)	79.24 ± 17.19	105.40 ± 5.27	0.045	80.34 ± 4.90	126.77 ± 9.51	< 0.001
GSH (μg/mg)	20.92 ± 2.28	26.30 ± 1.89	0.037	28.49 ± 4.51	45.15 ± 7.47	0.016
GSH-PX (U/mg prot)	0.020 ± 0.004	0.032 ± 0.002	0.006	0.022 ± 0.004	0.032 ± 0.006	0.043

Values are expressed as the mean ± SD (n = 6 per group)

MDA malondialdehyde, GSH glutathione, SOD superoxide dismutase, CAT catalase, GSH-Px glutathione peroxidase, H plateau hypoxia, P plain