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. 2022 Mar 2;12:3449. doi: 10.1038/s41598-022-07379-x

Figure 3.

Figure 3

Reduced locomotor activity in Adipo-KO mice. (A,B) Hourly average of O2 consumption (VO2) of Nrdcfl/fl and Adipo-KO mice at room temperature (A; 23 °C) and thermoneutrality (B; 30 °C). Data are shown as the mean ± standard deviation (SD). N = 6/genotype; P90. (C) Half day (Dark; 21:00–9:00, Light; 9:00–21:00) and full day (Total) average of VO2 at room temperature (23 °C) and thermoneutrality (30 °C). Data are shown as the mean ± SD. (D,E) Hourly average of the respiratory exchange rate (RER) of Nrdcfl/fl and Adipo-KO mice at room temperature (D; 23 °C) and thermoneutrality (E; 30 °C). Data are shown as the mean ± SD. N = 6/genotype; P90. (F) Half day (Dark; 21:00–9:00, Light; 9:00–21:00) and full day (Total) average of RER at room temperature (23 °C) and thermoneutrality (30 °C). Data are shown as the mean ± SD. (G,H) Hourly average of locomotor activity in Nrdcfl/fl and Adipo-KO mice at room temperature (G; 23 °C) and thermoneutrality (H; 30 °C). Data are shown as the mean ± SD. N = 6/genotype; P90. (I) Half day (Dark; 21:00–9:00, Light; 9:00–21:00) and full day (Total) average of locomotor activity at room temperature (23 °C) and thermoneutrality (30 °C). Data are shown as the mean ± SD, *p < 0.05. (J) Skin blood flow in the hindlimb of Nrdcfl/fl and Adipo-KO mice at room temperature measured by laser speckle flowmetry. Data are shown as the mean + SD. n. s.; not significant.