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. 2022 Feb 17;9:834725. doi: 10.3389/fmed.2022.834725

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Copyright © 2022 Tang, Hu, Niu, Sun and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Volcano map of dataset from the George cohort (Red dots represent upregulated genes, blue dots represent downregulated genes, and gray dots indicate no difference in expression). (B) Heat map of the DEGs identified from the George cohort. (C) Volcano map of the Jiang cohort. (D) Heat map of DEGs identified from the Jiang cohort. (E) Venn diagram. The intersection represents the upregulated genes in the high-score cohort of both datasets. (F) Venn diagram. The intersection represents the downregulated genes in the high-score cohort of both datasets.