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. 2022 Feb 17;13:815422. doi: 10.3389/fpsyt.2022.815422

Figure 2.

Figure 2

(A) HAMD-scores for patient 1 and 2 over time, including cut-offs for depressive symptom severity. (B) Change scores of HAMD rating for both patients at 4-weeks compared to baseline and 8-weeks compared to baseline. A higher (and positive) change score indicates improvement of depressive symptoms as the change score was calculated by subtracting the score at post-intervention from the score at baseline (e.g., baseline score: 21, post-intervention score: 9, equals 21–9 = 12). (C) GSRS-scores for both patients over time; without cut-off for GI-symptom severity as different clusters of symptoms are defined by the GSRS (e.g., constipation) and classification of severity would be only possible for each symptom, not for the overall score. (D) GSRS change scores for both patients at 4-weeks compared to baseline and 8-weeks compared to baseline. (E) BDI-II-scores for both patients over time. (F) BDI-II change scores for both patients at 4-weeks compared to baseline and 8-weeks compared to baseline.