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. 2022 Feb 26;10(6):1946–1951. doi: 10.12998/wjcc.v10.i6.1946

Table 1.

Characteristics of cryptogenic organizing pneumonia with pregnancy: Previous published case report

Case No. 1 2 3 4
Ref. Ghidini et al[1], 1999 Futagami et al[10], 2003 Holder et al[5], 2011 Present
Age (yr) 27 33 16 35
Underlying disease HIV ITP, asthma COP, pulmonary hypertension, asthma, partial right lower-lobe resection None
Gestational age (wk) at diagnosis 26 + 5 38 20 16 + 1
Gestational age (wk) at delivery 34 38 28 39+4
Symptoms Cough, dyspnea, chest pain Cough, fever Dyspnea, chest pain, fatigue Chest pain, cough, dyspnea, sputum
Radiologic Findings Diffuse bilateral parenchymal infiltrates (left lower lobe) in chest X-ray Diffuse bilateral parenchymal infiltrates in chest X-ray Patchy ground glass infiltrates in chest CT Multifocal patchy airspace consolidation and GGO
Initial diagnosis Asthmatic bronchitis or interstitial; Pneumonia Asthmatic bronchitis or mycoplasmic pneumonia Pre-existing COP CAP
Definite diagnosis method Open lung biopsy BAL, TBLB NA BAL, TBLB
Initial treatment Trimethoprim (300 mg) + sulfamethoxazole (1500 mg) IV every 6 h + ceftriaxone (2 g) IV daily, methylprednisolone, 60 mg IV every 8 h Cefmetazole 1 g every 12 h + gabexatemesilate 2 g IV continuously NA Ceftriaxone (2 g daily) IV + amoxicillin (250 mg every 8 h), cefpodoxime (100 mg every 12 h) orally
Final treatment Dexamethasone, 5 mg IV every 12 h for 72 h, folowed by methylprednisolone, 60 mg IV daily for 48 h, then 30 mg IV every 8 h for 4 d; and prednisone 40 mg/d orally Minocycline 100 mg + methylprednisolone 125 mg every 12 h and every 8 h, for 5 d, followed 40 mg per day orally for 11 d Nebulizer of a beta-2 agonist and corticosteroids Prednisolone (0.5 mg/kg/d) for 10 d

BAL: Bronchoalveolar lavage; CAP: Community acquired pneumonia; COP: Cryptogenic organizing pneumonia; GGO: Ground glass opacity; HIV: Human immunodeficiency virus; ITP: Immune thrombocytopenia; IV: Intravenous; NA: Not available; TBLB: Transbronchial lung biopsy; CT: Computed tomography.