Table 5.
Regression coefficients and p values for the EORTC QLQ-BR23 domains in which quadratic models were favored in the ITT population, with WPL as the dependent variable.
| Linear coefficient (β1) |
Quadratic coefficient (β2) |
|||||
|---|---|---|---|---|---|---|
| EORTC QLQ-BR23 item/domain | Sample size | MID for deterioration | Regression coefficient (95% CI) |
p value | Regression coefficient (95% CI) |
p value |
| Sexual Functioning | 325 | 11 | 2.50 (1.58, 3.42) |
<0.001 | 0.44 (0.21, 0.67) |
<0.001 |
| Systemic Therapy Side Effects | 329 | 10 | 5.31 (4.08, 6.55) |
<0.001 | 0.80 (0.32, 1.28) |
0.001 |
CI, confidence interval; EORTC QLQ-BR23, European Organisation for Research and Treatment of Cancer breast cancer–specific module; ITT, intent to treat; MID, minimally important difference; WPL, work productivity loss.
Domains in white background are functional components, and those in gray background are symptomatic components. Statistically significant p values are in bold text.