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. 2022 Feb 17;12:728996. doi: 10.3389/fmicb.2021.728996

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Copyright © 2022 Li, Ning, Zheng, Chu, Cui, Zhang, Guo, Wei, Liu, Sun, Ye, Jiang, Yuan, Li, Bian, Bell-Sakyi, Wang, Jiang, Song, Cao, Tsan-Yuk Lam, Ni and Jia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNAseq analysis of tick gene transcripts detected in pools of flat and fully fed I. persulcatus ticks removed from human patients at Mudanjiang Forestry Central Hospital in Heilongjiang Province, China. (A) Clustered heatmap of genes differentially expressed (DE) between flat and fully fed ticks. The top 10 most significant genes in the increasing and decreasing expression clusters are shown. The expression patterns of DE genes in each tick pool are shown for (B) upregulated genes and (C) downregulated genes.