Table 1.
Rate constants | Protein isoform |
|
---|---|---|
ASC | ASCb | |
k1a | 0.15 ± 0.03 | 0.02 ± 0.01 |
k2a | 0.04 ± 0.01 | 0.02 ± 0.01 |
k1avePYD | 0.21 ± 0.04 | 0.0269 ± 0.0009 |
k2avePYD | 0.05 ± 0.02 | 0.0269 ± 0.0009 |
k1aveCARD | 0.12 ± 0.02 | 0.0288 ± 0.0009 |
k2aveCARD | 0.02 ± 0.01 | 0.0288 ± 0.0009 |
Goodness of fit | ||
χ2 | 0.000327961 | 0.00059583 |
r | 0.999812 | 0.999806 |
Reported values are averaged and SD obtained from fitting the logistic equations to the RT-NMR data at ∼700 and 500 μΜ for each isoform. Units for rate constants are in h−1.