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. 2022 Jan 8;298(3):101566. doi: 10.1016/j.jbc.2022.101566

Table 1.

Kinetic parameters from logistic Equations 1 and 2

Rate constants Protein isoform
ASC ASCb
k1a 0.15 ± 0.03 0.02 ± 0.01
k2a 0.04 ± 0.01 0.02 ± 0.01
k1avePYD 0.21 ± 0.04 0.0269 ± 0.0009
k2avePYD 0.05 ± 0.02 0.0269 ± 0.0009
k1aveCARD 0.12 ± 0.02 0.0288 ± 0.0009
k2aveCARD 0.02 ± 0.01 0.0288 ± 0.0009
Goodness of fit
 χ2 0.000327961 0.00059583
 r 0.999812 0.999806
a

Reported values are averaged and SD obtained from fitting the logistic equations to the RT-NMR data at ∼700 and 500 μΜ for each isoform. Units for rate constants are in h−1.