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Front (upper panel) and top view (lower panel) of the NAMPT–TLR4 complex obtained by docking human NAMPT dimer (monomers are rendered as green and light green solid surfaces) onto homology modeled TLR4 (gray ribbon). NAMPT amino acids of the two monomers involved in the interaction with TLR4 are rendered as dark and light blue surfaces, respectively. α1-α2 and β1-β2 K-rich loops on NAMPT are highlighted in red and purple, respectively.
