FIG. 4.
Relationship between MIC, fluconazole dose, and emergence of resistance in oropharyngeal candidiasis. ○, MIC of fluconazole for the clinical isolate; ■, effective daily dose of fluconazole. MICs are represented on the secondary y axis, in logarithmic scale. Boxes above the graph represent genetic changes identified at each stage. Based on data from references 114 and 151.