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. 2022 Feb 17;13:813849. doi: 10.3389/fmicb.2022.813849

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Copyright © 2022 Leopold, Abdelraouf, Nicolau, Agresta, Johnson, Teter, Dunne, Broadwell, van Belkum, Schechter, Sodergren and Weinstock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Principal coordinate analysis (PCoA) of taxonomic profiles. PCoA analysis based on the Bray-Curtis distance matrix of OTUs from TZP1 (A) and TZP2 (B) experiments. Each circle represents a single mouse at a single time point. Closed circles represent mice that had >50% Clostridiales (OTU-1 in A, OTU-3 in B) at any time point and open circles represent all other mice. (C) PCoA analysis on Bray-Curtis distance matrix based on combined genera profiles from both experiments. Note that the number of bullets per panel may vary as a consequence of the number of mice per group and the number of samples taken and analyzed in full per individual mouse.