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. 2022 Feb 17;13:813849. doi: 10.3389/fmicb.2022.813849

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Copyright © 2022 Leopold, Abdelraouf, Nicolau, Agresta, Johnson, Teter, Dunne, Broadwell, van Belkum, Schechter, Sodergren and Weinstock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Resistant Clostridiales OTUs. The fold change of relative abundance of Clostridiales OTUs 1 and 3, (A,B, TZP1 and TZP2, respectively) compared to the last pre-antibiotic time point (Days 6 and 14, respectively) are plotted for each day. The vertical line indicates the approximate first TZP exposure. Mice 1–10 were immunocompetent while mice 11–20 were neutropenic.