Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 17;10:816576. doi: 10.3389/fchem.2022.816576

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Li, Yang, Blankenship, Cho, Xu, Wang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Initial screening of Mpro inhibition by selected compounds from docking. Tested compounds are selected from (A) the batch selected with affinity from receptor-rigid docking, (B) the batch selected with binding energy vs. molecular weight from receptor-rigid docking, and (C) the batch selected from receptor-flexible docking. 100, 10 and 1 µM were used for each inhibitor to perform the inhibition assay. Fluorescence intensity was monitored with respect to the control that had no inhibitor provided.