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. 2022 Feb 25;119(9):e2118818119. doi: 10.1073/pnas.2118818119

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Copyright © 2022 the Author(s). Published by PNAS.

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Fig. 6. — Kurarinone inhibited the sEH activity in vitro and interacted with sEH. (A) IC₅₀ plot of kurarinone against sEH. (B) Michaelis-Menten plot of kurarinone against sEH. (C) Lineweaver-Burk plot of kurarinone against sEH. (D) SPR plot of kurarinone with sEH. (E) Kurarinone bound to the cavity of sEH (PDB code 7EBA). (F) Electronic cloud plot of kurarinone and the interaction of kurarinone with sEH. (G) Interaction differences of kurarinone (cyan) and TPPU (yellow, PDB code 4OCZ) with sEH. CTRL, control.