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Typhoid infection and natural history. Boxes indicate compartments and arrows indicate transitions between compartments (new infections are further delineated via dashed arrows). Compartment abbreviations are as follows: C, carrier; IC, clinically infected; IS, subclinically infected; R, recovered; S, susceptible; V, vaccinated. New infections (transitions to the IC or IS compartments) are designated with dashed lines. Details are shown in the Supplementary Technical Appendix.
