Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 24;47(4):81. doi: 10.3892/or.2022.8292

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Shan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Effects of VSCC-SCs, SCC-SCs and HDFs on the invasion of HSC-3 cells in bone invasion regions. IHC was used to determine the expression levels of (A) MMP9 and (B) MT1-MMP. Semi-quantification of (C) MMP9 and (D) MT1-MMP expression levels in bone invasion regions of HSC-3 cells. Data are shown as the median and IQR, n=4. Statistical analysis was performed by Kruskal-Wallis test followed by Dunn's test. ^nsP>0.05, *P<0.05, **P<0.01, ****P<0.0001 vs. HSC-3 or as indicated. HDFs, human dermal fibroblasts; MMP, matrix metalloproteinase; IHC, immunohistochemistry; MT1-MMP, membrane-type 1 MMP; SCC-SC, squamous cell carcinoma-associated stromal cells; VSCC-SC, verrucous squamous cell carcinoma-associated stromal cells.