Table 1. Alkaline Phosphatase Inhibitory Activity of Synthesized Compoundsa.
| compound codes | alkaline phosphatase IC50 SEM (μM) |
|---|---|
| 3a | NAb |
| 3b | 8.234 ± 0.265 |
| 3c | 5.356 ± 0.079 |
| 3d | 4.768 ± 0.149 |
| 3e | 6.564 ± 0.210 |
| 3f | 2.502 ± 0.023 |
| 3g | 11.342 ± 0.290 |
| 3h | 4.169 ± 0.154 |
| 3i | NAb |
| 3j | 9.436 ± 0.243 |
| 3k | 6.306 ± 0.179 |
| 4a | 7.678 ± 0.267 |
| 4b | 8.723 ± 0.132 |
| 4c | NAb |
| 4d | 1.271 ± 0.0410 |
| 4e | 2.943 ± 0.121 |
| 4f | 6.543 ± 0.129 |
| 4g | NAb |
| 4h | 3.439 ± 0.139 |
| 4i | 2.132 ± 0.034 |
| 4j | 4.876 ± 0.086 |
| 4k | NAb |
| KH2PO4 | 2.80 ± 0.065 |
a
Values are presented as mean ± standard error of mean (SEM).
b
NA - No activity.