Table 3.
Variables | Live birth | Clinical pregnancy | ||||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | P-value |
Adjusted OR (95% CI)a |
P-valuea | OR (95% CI) | P-value |
Adjusted OR (95% CI)a |
P-valuea | |
Group | ||||||||
Low-AMH | 0.620 (0.504–0.762) | < 0.001 | 0.910 (0.710–1.166) | 0.455 | 0.616 (0.497–0.763) | < 0.001 | 0.843 (0.653–1.089) | 0.191 |
Average-AMH | 0.840 (0.702–1.006) | 0.057 | 0.943 (0.776–1.148) | 0.561 | 0.788 (0.652–0.953) | 0.014 | 0.863 (0.703–1.060) | 0.160 |
High-AMH | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Female age (y) | 0.938 (0.921–0.956) | < 0.001 | 0.958 (0.938–0.978) | < 0.001 | 0.949 (0.930–0.968) | < 0.001 | 0.970 (0.950–0.991) | 0.005 |
Female BMI (kg/m2) | 1.001 (0.998–1.004) | 0.553 | 1.001 (0.997–1.005) | 0.590 | ||||
Duration of infertility (y) | 0.980 (0.953–1.007) | 0.148 | 0.987 (0.959–1.016) | 0.383 | ||||
Total dose of gonadotropin used (IU)1 | 0.750 (0.677–0.831) | < 0.001 | 0.907 (0.804–1.023) | 0.111 | 0.756 (0.680–0.840) | < 0.001 | 0.900 (0.796–1.018) | 0.094 |
Serum E2 level (pg/mL) on hCG day2 | 1.128 (1.074–1.184) | < 0.001 | 1.035 (0.976–1.099) | 0.253 | 1.079 (1.026–1.135) | 0.003 | 0.971 (0.913–1.032) | 0.341 |
Endometrial thickness (mm) on hCG day | 1.088 (1.053–1.124) | < 0.001 | 1.089 (1.052–1.126) | < 0.001 | 1.088 (1.052–1.126) | < 0.001 | 1.088 (1.050–1.127) | < 0.001 |
No. of oocyte fertilized | 1.076 (1.056–1.098) | < 0.001 | 1.030 (1.004–1.056) | 0.022 | 1.077 (1.055–1.099) | < 0.001 | 1.043 (1.016–1.070) | 0.002 |
No. of embryos transferred | 0.891 (0.780–1.018) | 0.089 | 0.907 (0.790–1.042) | 0.168 | ||||
Embryo type | ||||||||
Cleavage embryo | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Blastocyst | 2.126 (1.824–2.477) | < 0.001 | 1.851 (1.567–2.187) | < 0.001 | 2.095 (1.782–2.462) | < 0.001 | 1.839 (1.543–2.193) | < 0.001 |
Embryo quality | ||||||||
Cycle with high-quality embryos | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Cycles without high-quality embryos | 0.309 (0.211–0.453) | < 0.001 | 0.313 (0.211–0.465) | < 0.001 | 0.339 (0.239–0.482) | < 0.001 | 0.341 (0.236–0.491) | < 0.001 |
Note: All the variables inputted in the model were shown in Table 3. BMI Body mass index, CI Confidence interval, OR Odds ratio, E2 Estradiol, hCG human chorionic gonadotropin, REF Reference, 1 per 1000 IU increased, 2 per 1000 pg/mL increased
aAdjusted for maternal age, total dose of gonadotropin used, serum E2 level and endometrial thickness on the day of ovulatory dose of hCG, number of fertilization, embryo type and embryo quality