Table 5.
Variables | Live birth | Clinical pregnancy | ||||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | P-value |
Adjusted OR (95% CI)a |
P-valuea | OR (95% CI) | P-value |
Adjusted OR (95% CI)a |
P-valuea | |
Group | ||||||||
Low-AMH | 1.440 (0.830–2.500) | 0.195 | 1.370 (0.750–2.502) | 0.306 | 1.123 (0.627–2.012) | 0.696 | 1.016 (0.544–1.901) | 0.959 |
Average-AMH | 1.147 (0.713–1.845) | 0.571 | 1.045 (0.630–1.734) | 0.863 | 1.318 (0.790–2.199) | 0.290 | 1.225 (0.717–2.093) | 0.459 |
High-AMH | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Female age (y) | 0.955 (0.904–1.009) | 0.098 | 0.928 (0.872–0.986) | 0.017 | 0.957 (0.902–1.016) | 0.149 | 0.934 (0.875–0.998) | 0.043 |
Female BMI (kg/m2) | 1.002 (0.996–1.007) | 0.583 | 1.003 (0.980–1.026) | 0.809 | ||||
Duration of infertility (y) | 0.985 (0.912–1.063) | 0.696 | 1.000 (0.920–1.087) | 0.999 | ||||
Total dose of gonadotropin used (IU)1 | 1.035 (0.802–1.335) | 0.794 | 1.100 (0.828–1.460) | 0.511 | ||||
Serum E2 level (pg/mL) on hCG day2 | 1.212 (1.066–1.379) | 0.003 | 1.103 (0.963–1.263) | 0.158 | ||||
Endometrial thickness (mm) on hCG day | 1.104 (1.008–1.209) | 0.034 | 1.094 (0.990–1.208) | 0.077 | 1.078 (0.977–1.191) | 0.135 | 1.064 (0.958–1.183) | 0.248 |
No. of oocyte fertilized | 1.054 (1.002–1.108) | 0.042 | 1.014 (0.960–1.071) | 0.626 | 1.057 (1.001–1.117) | 0.046 | 1.011 (0.954–1.071) | 0.711 |
No. of embryos transferred | 0.907 (0.591–1.391) | 0.654 | 1.916 (1.094–3.358) | 0.023 | 0.860 (0.538–1.373) | 0.527 | 1.871 (1.007–3.476) | 0.048 |
Embryo type | ||||||||
Cleavage embryo | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Blastocyst | 2.747 (1.812–4.164) | < 0.001 | 3.488 (2.023–6.013) | < 0.001 | 2.790 (1.742–4.468) | < 0.001 | 3.659 (1.970–6.795) | < 0.001 |
Embryo quality | ||||||||
Cycle with high-quality embryos | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
Cycles without high-quality embryos | 0.158 (0.034–0.742) | 0.019 | 0.172 (0.035–0.841) | 0.030 | 0.332 (0.099–1.110) | 0.073 | 0.423 (0.120–1.488) | 0.180 |
Note: All the variables inputted in the model were shown in Table 5. BMI Body mass index, CI Confidence interval, OR Odds ratio, E2 Estradiol, hCG human chorionic gonadotropin, Ref Reference, 1 per 1000 IU increased, 2 per 1000 pg/mL increased
aAdjusted for maternal age, endometrial thickness on the day of ovulatory dose of hCG, number of fertilization, number of embryos transferred, embryo type and embryo quality