Table 2.
Location profile of NMOSD attacks
| Location profile | NMOSD–AQP4+ (N = 121) | NMOSD–MOG+ (N = 67) | NMOSD–DN (N = 23) | Total (N = 211) |
|---|---|---|---|---|
| Isolated myelitis | 66 (71.0%) | 17 (18.3%) | 10 (10.8%) | 93 (44%) |
| Isolated optic neuritis | 34 (46.6%) | 35 (47.9%) | 4 (5.5%) | 73 (35%) |
| Isolated brainstem | 5 (71.4%) | 2 (28.6%) | 0 (0%) | 7 (3.3%) |
| Isolated encephalitis | 0 (0%) | 2 (100%) | 0 (0%) | 2 (0.9%) |
| Myelitis + optic neuritis (Neuromyelitis optica) | 6 (37.5%) | 5 (31.3%) | 5 (31.3%) | 16 (8%) |
| Optic neuritis + brainstem | 0 (0%) | 0 (0%) | 1 (100%) | 1 (0.5%) |
| Optic neuritis + encephalitis | 0 (0%) | 1 (100%) | 0 (0%) | 1 (0.5%) |
| Myelitis + encephalitis | 1* (100%) | 0 (0%) | 0 (0%) | 1 (0.5%) |
| Myelitis + brainstem | 6 (54.5%) | 4 (36.4%) | 1 (9.1%) | 11 (5.2%) |
| Myelitis + optic neuritis + brainstem | 1 (25.0%) | 1 (25.0%) | 2 (50.0%) | 4 (1.9%) |
| Myelitis + brainstem + encephalitis | 1* (100%) | 0 (0%) | 0 (0%) | 1 (0.5%) |
| Myelitis + optic neuritis + brainstem + encephalitis | 1* (100%) | 0 (0%) | 0 (0%) | 1 (0.5%) |
Neuromyelitis optica spectrum disorder presentations and their serotypes. Nine attacks were multifocal, including 3 cases of NMOSD–AQP4+ acute demyelinating encephalomyelitis (*). Categorical variables are presented as count (percentage). Percentages are in the column axis for the “Total” column and in the row axis for the others
NMOSD–AQP4+: NMOSD attacks with anti-AQP4 antibodies; NMOSD–MOG+: NMOSD attacks with anti-MOG antibodies; NMOSD–DN: double seronegative NMOSD attacks