Table 2.
Surgery and anesthesia data of subjects without and with CPSP (n = 2348)
| Variables | Non-CPSP (n = 1315) | CPSP (n = 1033) | P value |
|---|---|---|---|
| Anesthesia, n (%) | |||
| General anesthesia | 965 (73.4) | 771 (74.6) | 0.492 |
| Combined with nerve block | 350 (26.6) | 262 (25.4) | |
| Fentanyl dosage (μg/kg) | 11.3 ± 4.8 | 11.0 ± 4.3 | 0.044 |
| Remifentanil dosage (μg/kg) | 11.8 ± 10.1 | 12.1 ± 9.3 | 0.478 |
| Dexmedetomidine usage, n (%) | 1214 (92.3) | 960 (92.9) | 0.573 |
| Sevoflurane usage, n (%) | 221 (16.8) | 199 (19.3) | 0.123 |
| PCIA, n (%) | 955 (72.6) | 763 (73.9) | 0.501 |
| Surgical Procedure, n (%) | |||
| Lung | 1235 (93.9) | 967 (93.6) | 0.179 |
| Mediastinal | 76 (5.8) | 57 (5.5) | |
| Others | 4 (0.3) | 9 (0.9) | |
| Lymph node dissection, n (%) | 603 (56.2) | 470 (43.8) | 0.863 |
| Duration of surgery (min) | 106.4 ± 47.6 | 107.9 ± 44.9 | 0.189 |
| Blood loss (ml/kg) | 2.0 ± 4.1 | 1.8 ± 3.5 | 0.013 |
| Infusion volume (ml/kg) | 22.7 ± 8.8 | 22.1 ± 8.0 | 0.114 |
| Consumption of rescue analgesia postoperative, n (%) | |||
| 450 (34.2) | 411 (39.8) | 0.005 | |
| Consumption of sedative hypnotic postoperative, n (%) | |||
| 22 (1.7) | 32 (3.1) | 0.022 | |
| Subcutaneous emphysema postoperative, n (%) | |||
| 210 (16.0) | 185 (17.9) | 0.212 | |
| History of postoperative wound infection, n (%) | |||
| 12 (0.9) | 57 (5.5) | < 0.001 | |
| Postoperative pulmonary infection, n (%) | |||
| 31 (2.4) | 37 (3.6) | 0.079 | |
| Postoperative WBC (109) | 11.4 ± 3.1 | 11.3 ± 3.3 | 0.202 |
| Postoperative CRP (mg/L) | 52.9 ± 1.0 | 51.1 ± 1.1 | 0.205 |
| PONV, n (%) | 180 (13.7) | 149 (14.4) | 0.610 |
bold: P< 0.05
PCIA postoperative patient-controlled intravenous analgesia, WBC white blood cell, CRP C-reactive protein, PONV postoperative nausea and vomiting