Table 2.

Univariate and multivariate Cox regression analysis of clinical pathologic features for OS in TCGA

	TCGA cohort
	Univariate analysis			Multivariate analysis
Characteristics	P-value	HR	95% CI	P-value	HR	95% CI
Age	< 0.001	1.073	1.061–1.084	< 0.001	1.066	1.049–1.084
Gender	0.462	0.9	0.681–1.191	0.68	1.08	0.749–1.559
Grade	< 0.001	3.093	2.637–3.628	0.028	1.33	1.032–1.714
Subtype	< 0.001	2.004	1.765–2.275	0.11	1.194	0.961–1.484
IDH	< 0.001	8.561	6.228–11.768	0.17	1.616	0.814–3.21
MGMT promoter	< 0.001	0.228	0.139–0.376	0.026	0.508	0.28–0.921
1p/19q	< 0.001	2.964	2.17–4.047	0.5	1.165	0.748–1.816
Risk score	< 0.001	1.126	1.099–1.154	0.007	1.066	1.018–1.117