Table 1.
Characteristics of patients with psychiatric disorders and severe COVID-19 receiving or not receiving FIASMA psychotropic medications at baseline (N = 545).
| Exposed to any FIASMA (N = 164) | Not exposed to any FIASMA (N = 381) | Non-exposed matched group (N = 164) | Exposed to any FIASMA vs. Not exposed | Exposed to any FIASMA vs. Not exposed | Exposed to any FIASMA vs. Non-exposed matched group | |
|---|---|---|---|---|---|---|
| Crude analysis | Analysis weighted by inverse-probability- weighting weights | Matched analytic sample analysis | ||||
| N (%) | N (%) | N (%) | SMD | SMD | SMD | |
| Age | 0.197 | 0.037 | 0.022 | |||
| 18 to 50 years | 19 (11.6%) | 26 (6.82%) | 18 (48.6%) | |||
| 51 to 70 years | 43 (26.2%) | 105 (27.6%) | 43 (50.0%) | |||
| 71 to 80 years | 37 (22.6%) | 75 (19.7%) | 38 (50.7%) | |||
| More than 80 years | 65 (39.6%) | 175 (45.9%) | 65 (50.0%) | |||
| Sex | 0.260 | 0.008 | 0.159 | |||
| Women | 90 (54.9%) | 160 (42.0%) | 77 (46.1%) | |||
| Men | 74 (45.1%) | 221 (58.0%) | 87 (54.0%) | |||
| Hospital | 0.267 | 0.024 | 0.068 | |||
| AP-HP Centre – Paris University, Henri Mondor University Hospitals and at home hospitalization | 36 (22.0%) | 115 (30.2%) | 40 (52.6%) | |||
| AP-HP Nord and Hôpitaux Universitaires Paris Seine-Saint-Denis | 45 (27.4%) | 77 (20.2%) | 46 (50.5%) | |||
| AP-HP Paris Saclay University | 41 (25.0%) | 113 (29.7%) | 38 (48.1%) | |||
| AP-HP Sorbonne University | 42 (25.6%) | 76 (19.9%) | 40 (48.8%) | |||
| Obesitya | 0.129 | 0.001 | 0.162 | |||
| Yes | 42 (25.6%) | 77 (20.2%) | 31 (42.5%) | |||
| No | 122 (74.4%) | 304 (79.8%) | 133 (52.2%) | |||
| Number of medical conditionsb | 0.321 | 0.015 | 0.029 | |||
| 0 | 42 (25.6%) | 51 (13.4%) | 40 (48.8%) | |||
| 1 | 17 (10.4%) | 37 (9.71%) | 17 (50.0%) | |||
| 2 or more | 105 (64.0%) | 293 (76.9%) | 107 (50.5%) |
a Defined as having a body-mass index higher than 30 kg/m2 or an International Statistical Classification of Diseases and Related Health Problems (ICD-10) diagnosis code for obesity (E66.0, E66.1, E66.2, E66.8, E66.9).
b Assessed using ICD-10 diagnosis codes for diabetes mellitus (E11), diseases of the circulatory system (I00-I99), diseases of the respiratory system (J00-J99), neoplasms (C00-D49), diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D5-D8), frontotemporal dementia (G31.0), peptic ulcer (K27), diseases of liver (K70-K95), hemiplegia or paraplegia (G81-G82), acute kidney failure or chronic kidney disease (N17-N19), and HIV (B20).
SMD > 0.1 in bold indicate substantial differences.
SMD standardized mean difference.